My main point is to understand if we could?Only one sure way to find out. built it!Interesting project!
I would consider AUW and flight time goal the determining factors.
34 pound thrust (30×10 pitch prop and 12S batt)
AUW 100 pounds
They claim a Quad with AUW of 55 pounds and 22,000mAh run time is between 10-20min while a Hexa with AUW of 66 pounds and 44,000mAh run time is between 30-40min
Link where I found specs
With asymmetric blades and around 1500rpm you are looking at 5S LiPo and at least 30,000mA which is at least 4 to 6 batts in parallel.
Surely a DJI phantom 4 has got to have its merits with 20min plus flying times. Why is this not an option?
~~Enjoying the hobby one flight at a time~~